ABOUT VYZULTA

VYZULTA is a prescription eye drop that may help reduce eye pressure in people with open-angle glaucoma or ocular hypertension.

How does VYZULTA work to control eye pressure?

VYZULTA helps lower eye pressure by increasing drainage of fluid from the eye. It is believed to work through 2 different pathways in the eye. Lowering eye pressure can help reduce the risk of vision loss due to glaucoma.

How is VYZULTA different from other eye drops?

VYZULTA is the only eye drop that delivers both nitric oxide and latanoprost acid to help open up constricted tissue so fluid in the eye can drain from both pathways.

People with glaucoma have 40% fewer nitric oxide markers in their eyes compared to those without the condition, which is why nitric oxide may be important for managing glaucoma. It is believed that when your eye has low levels of nitric oxide, the main pathway that allows the eye to drain becomes tense and constricted.

How nitric oxide works on the main outflow pathway

(Demonstrating only one part of the mechanism of action)

Image of Main Drainage PathwayImage of Main Drainage Pathway

  • Constricted tissue reduces fluid drainage

  • VYZULTA has nitric oxide which helps open up constricted tissue

  • Tissue relaxes and opens up to reduce eye pressure so fluid in the eye can drain

Opened pathway and improved eye drainage animation with the help of nitric oxide. Opened pathway and improved eye drainage animation with the help of nitric oxide.

WATCH
Outflow pathways:
Why treating both is
important to lowering
eye pressure

Video: Why treating both is important to lowering eye pressure
Drop icon.

Unlike other eye drops, VYZULTA works on 2 pathways
to promote fluid drainage.

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Eligible* commercially insured patients may
pay as little as a 
 $35 COPAY† FOR UP TO
A 90-DAY SUPPLY For first Rx and eligible refills

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How can I get VYZULTA?

How can I get VYZULTA?

This treatment is available through a prescription from your doctor. Ask your doctor if VYZULTA is right for you.

Is there a generic substitute for VYZULTA?

Is there a generic substitute for VYZULTA?

There is no generic equivalent for VYZULTA. You have been prescribed VYZULTA because your doctor believes this treatment is appropriate for you. If you are asked by your pharmacist to substitute your VYZULTA prescription, you should contact your eye doctor.

What are the possible side effects of VYZULTA?

What are the possible side effects of VYZULTA?

The most common side effects seen in studies were eye redness, eye irritation, eye pain, and pain after putting the drops in your eye. These are not all of the possible side effects.

Brown color, or increased brown color, of the iris can occur, which may be permanent. Darkening of the eyelid skin may also occur, which is usually reversible after VYZULTA treatment is discontinued.

Gradual changes to eyelashes may occur, including increased length, thickness, color, number of eyelashes, and/or change in direction of eyelash growth. These changes may result in a difference in the appearance of each eye. These changes are usually reversible after VYZULTA treatment is discontinued.

Please see Important Safety Information below.

Call your doctor immediately if you:

  • Experience any change in your eye
  • Develop any new eye conditions
  • Experience any sudden change in your vision or any eye side effects
  • Have eye surgery

VYZULTA works differently to help lower eye pressure.

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INDICATION

VYZULTA® (latanoprostene bunod ophthalmic solution), 0.024%, is used to lower intraocular (eye) pressure in patients with open-angle glaucoma or ocular hypertension.

IMPORTANT SAFETY INFORMATION

  • Brown color, or increased brown color, of the iris can occur, which may be permanent. Darkening of the eyelid skin may also occur, which is usually reversible after VYZULTA treatment is discontinued.
  • Gradual changes to eyelashes may occur, including increased length, thickness, color, number of eyelashes and/or direction of eyelash growth. These changes may result in a difference in appearance of each eye. These changes are usually reversible after VYZULTA treatment is discontinued.
  • Avoid touching the tip of the container to the eye or any other surface, including a finger, in order to avoid contamination of the solution by bacteria. Serious damage to the eye and possible loss of vision may result from using contaminated solutions.
  • Tell your doctor immediately about any change in your eye, any eye condition that develops, any sudden change in your vision, any eye side effects, or if you have eye surgery.
  • Remove contact lenses before putting VYZULTA in your eyes. Lenses may be reinserted 15 minutes later.
  • If you are using other eye drops in addition to VYZULTA, wait 5 minutes between using each type of eye drop.
  • The most common side effects seen in studies were eye redness, eye irritation, eye pain, and pain after putting the drops in your eye.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click here to see full Prescribing Information.

*Offer not valid for patients whose prescriptions are reimbursed by any federal or state healthcare program, including Medicaid, Medicare, TRICARE, or any other federal or state healthcare program. Other restrictions apply. See complete Eligibility Criteria and Terms and Conditions at BauschCopayProgram.com. Ninety-day supply to be prescribed as 3 bottles of 2.5 mL solution each. Ninety-day supply copay offer only applies if each of the three 2.5-mL bottles is covered by a patient’s commercial insurance.
†Exclusively at Walgreens and other participating independent pharmacies, eligible commercially insured patients may pay as little as a $25 copay.
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INDICATION

VYZULTA® (latanoprostene bunod ophthalmic solution), 0.024%, is used to lower intraocular (eye) pressure in patients with open-angle glaucoma or ocular hypertension.

IMPORTANT SAFETY INFORMATION

  • Brown color, or increased brown color, of the iris can occur, which may be permanent. Darkening of the eyelid skin may also occur, which is usually reversible after VYZULTA treatment is discontinued.